
Ipamorelin (10 mg Vial)
Ipamorelin is a synthetic pentapeptide that acts as a selective growth hormone secretagogue by mimicking ghrelin at the GH secretagogue receptor. Its key advantage is high specificity for GH release without triggering ACTH or cortisol elevation, making it one of the safer GH secretagogues with minimal off-target hormonal effects. This educational protocol presents a once-daily subcutaneous approach using practical dilution for precise insulin-syringe measurements.
- Dose
- 0.2–0.3 mg per injection
- Frequency
- 2–3 times daily
- Timing
- Morning, post-workout, before bed
- Duration
- 8–12 weeks
Selective GH secretagogue. Minimal cortisol/prolactin elevation. Excellent safety profile.
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
|---|---|---|
| Weeks 1–2 | 100 mcg | 3 units (0.03 mL) |
| Weeks 3–4 | 150 mcg | 5 units (0.05 mL) |
| Weeks 5–8 | 200 mcg | 6 units (0.06 mL) |
| Weeks 9–12 | 250 mcg | 8 units (0.08 mL) |
- •Peptide Vials (Ipamorelin, 10 mg each):
- •Insulin Syringes (U-100):
- •Bacteriostatic Water (10 mL bottles): Use ~3.0 mL per vial for reconstitution.
- •Alcohol Swabs: One for the vial stopper + one for the injection site each day.
Translational Andrology and Urology (PMC)
Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males (2020 review)
View sourceEuropean Journal of Endocrinology (PubMed)
Ipamorelin, the first selective growth hormone secretagogue (1998 preclinical pharmacology study)
View sourceEuropean Journal of Anatomy
Chronic in vivo Ipamorelin treatment stimulates body weight gain and growth hormone (GH) release in vitro in young female rats (2002 animal study on chronic dosing)
View sourcePharmaceutical Research (PubMed)
Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers (1999 Phase I clinical pharmacology study)
View sourceEuropean Journal of Anatomy
Three-week chronic in vivo ipamorelin treatment: no desensitization of GH release mechanisms (2002 animal study)
View sourceInternational Journal of Colorectal Disease (PubMed)
Prospective, randomized, controlled, proof-of-concept study of the ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients (2014 Phase II clinical trial)
View sourceJohns Hopkins Arthritis Center
How to Give a Subcutaneous Injection (patient educational resource)
View sourceNCBI Bookshelf
Best practices for injection: asepsis, preparation, and administration techniques
View sourcePharmacologic Considerations (PMC)
Subcutaneous drug injection: review of pharmacologic considerations and site rotation practices
View sourceNIBSC (National Institute for Biological Standards)
Peptide Handling, Dissolution & Storage Guidelines (peptide storage recommendations)
View sourceBachem (Peptide Manufacturer)
Handling and Storage Guidelines for Peptides (technical best-practices)
View sourceCreative Peptides
How Long Do Peptides Last? Peptide Stability & Shelf Life (technical article on peptide stability)
View source
Educational content adapted from peptidedosages.com. Not medical advice.