Peptide Companion
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Peptide Companion
single
Anti-Aging
Vial: 10 mg

Epitalon (Epithalon) (10 mg Vial)

Epitalon (Epithalon) dosage protocols center on this synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed from pineal gland research for its geroprotective potential. Epitalon activates telomerase to promote telomere elongation, supports healthy melatonin production for improved sleep and circadian rhythm regulation, and has demonstrated lifespan extension in animal models. Human studies suggest potential benefits for longevity, cardiovascular health, and physiological function in older adults. This educational protocol presents a once-daily subcutaneous approach using a practical dilution for clear insulin-syringe measurements.

Dose
5–10 mg per injection
Frequency
Once daily or every other day
Timing
Evening preferred
Duration
10–20 days, cycled

Telomerase activator. Anti-aging research. Typical cycle: 10-20 days, repeated 2-4 times yearly.

Dosing Schedule
PhaseDaily Dose (mcg)Units (per injection) (mL)
Days 1–20 (Cycle On)5,000 mcg (5 mg)100 units (1.00 mL)
Weeks 4–26 (Cycle Off)0 mcg—
Supplies Needed
  • •Peptide Vials (Epitalon, 10 mg each):
  • •Insulin Syringes (U-100):
  • •Bacteriostatic Water (10 mL bottles): Use 2.0 mL per vial for reconstitution.
  • •Alcohol Swabs: One for the vial stopper + one for the injection site each day.
References

  • Int J Mol Sci (MDPI)

    Overview of Epitalon: Highly Bioactive Pineal Tetrapeptide with Promising Properties (2025)

    View source

  • PMC/Biogerontology

    Epitalon increases telomere length in human cell lines through telomerase upregulation

    View source

  • Neuroendocrinology Letters (PubMed)

    Synthetic tetrapeptide Epitalon restores neuroendocrine regulation in senescent monkeys

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  • Bull Exp Biol Med (PubMed)

    Geroprotective effect of epithalamine in elderly with accelerated aging (12-year RCT)

    View source

  • Alzheimer’s Drug Discovery Foundation

    Epithalamin/Epithalon Cognitive Vitality Report (mechanisms, dosing, safety)

    View source

  • JPT Peptide Technologies

    Peptide Stability: How Long Do Peptides Last? (storage best practices)

    View source

  • Tydes Laboratory

    Bacteriostatic Water and Peptide Reconstitution (28-day use guideline)

    View source

  • Johns Hopkins Arthritis Center

    How to Give a Subcutaneous Injection (patient education guide)

    View source

  • Wikipedia

    Epitalon (overview of Hayflick limit studies and telomerase activation)

    View source

  • CDC

    Vaccine administration: subcutaneous route (angle/site; no aspiration)

    View source

  • Immunize.org (IAC)

    How to Administer Subcutaneous Injections (CDC-backed guidelines)

    View source

  • NCBI Bookshelf

    Best practices for injection (asepsis, preparation, and administration)

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  • Subcutaneous Drug Injection Review (PMC)

    Pharmacologic considerations of the subcutaneous route

    View source

Educational content adapted from peptidedosages.com. Not medical advice.