
Gonadorelin (2 mg Vial)
Gonadorelin dosage supports the restoration of natural LH and FSH release from the pituitary gland, reactivating the hypothalamic‑pituitary‑gonadal (HPG) axis. As a synthetic form of gonadotropin‑releasing hormone (GnRH), gonadorelin stimulates testosterone production in men and promotes ovulation in women when administered in short, pulsatile doses. This educational protocol outlines a subcutaneous micro‑dosing approach using a practical dilution for accurate insulin‑syringe measurements.
- Dose
- 0.1–0.2 mg per injection
- Frequency
- 2–3 times weekly
- Timing
- Any time of day
- Duration
- Research protocol specific
Stimulates LH/FSH release. HPG axis research. Pulsatile administration may be beneficial.
| Week/Phase | Dose per Injection (mcg) | Units (mL) |
|---|---|---|
| Weeks 1–2 (Initiation) | 50 mcg | 5 units (0.05 mL) |
| Weeks 3–4 (Titration) | 100 mcg | 10 units (0.10 mL) |
| Weeks 5–8 (Maintenance) | 100–150 mcg | 10–15 units (0.10–0.15 mL) |
- •Peptide Vials (Gonadorelin, 2 mg each):
- •Insulin Syringes (U‑100, 30‑ or 50‑unit preferred):
- •Bacteriostatic Water (10 mL bottles): Use 2.0 mL per vial for reconstitution.
- •Alcohol Swabs: One for the vial stopper + one for the injection site each administration.
PubMed
GnRH agonists: gonadorelin, leuprolide, and nafarelin – overview of pharmacology and clinical applications
View sourceMayo Clinic
Gonadorelin injection routes and indications for LH/FSH stimulation testing
View sourceWikipedia
Gonadorelin pharmacology, pulsatile dosing, and clinical history
View sourcePMC
Gonadotropin‑releasing hormone analogs: pulsatile vs. continuous effects on FSH/LH
View sourcePubMed
Gonadotropin treatment for male hypogonadotropic hypogonadism – spermatogenesis and fertility
View sourceScienceDirect
Gonadorelin agonist overview: initial stimulation and subsequent down‑regulation mechanisms
View sourcePMC
Preserving fertility in the hypogonadal patient: hCG and GnRH therapy options
View sourcePMC
Pulsatile gonadorelin pump induces earlier spermatogenesis in congenital HH men
View sourcePubMed
Application of GnRH in hypogonadotropic hypogonadism: diagnostic and therapeutic aspects
View sourceDrugs.com
Gonadorelin injectable: uses, side effects, and warnings
View sourcePMC
Subcutaneous drug injection review: pharmacologic considerations
View sourceCDC
Vaccine administration: subcutaneous route (angle/site; no aspiration)
View sourceCDC (Subcut Injection PDF)
Technique diagram and site guidance for subcutaneous injections
View sourceNCBI Bookshelf
Best practices for injection (asepsis, preparation, and administration)
View source
Educational content adapted from peptidedosages.com. Not medical advice.