Peptide Companion
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Peptide Companion
single
Healing & Recovery
Vial: 5 mg

LL-37 (5 mg Vial)

LL-37 (also known as CAP-18) is a 37-amino-acid cationic antimicrobial peptide derived from the C-terminal of human cathelicidin (hCAP18). It is the only known human cathelicidin, exhibiting broad-spectrum antibacterial activity and immune-modulating properties. This educational protocol presents a once-daily subcutaneous approach using a practical dilution for clear insulin-syringe measurements.

Detailed protocol below.

Dosing Schedule
WeekDaily Dose (µg)Units (per injection) (mL)
Week 150 µg3 units (0.03 mL)
Week 2100 µg6 units (0.06 mL)
Week 3150 µg9 units (0.09 mL)
Week 4200 µg12 units (0.12 mL)
Week 5250 µg15 units (0.15 mL)
Week 6300 µg18 units (0.18 mL)
Week 7350 µg21 units (0.21 mL)
Week 8400 µg24 units (0.24 mL)
Supplies Needed
  • •Peptide Vials (LL-37, 5 mg each):
  • •Insulin Syringes (U-100):
  • •Bacteriostatic Water (10 mL bottles): Use ~3.0 mL per vial for reconstitution.
  • •Alcohol Swabs: One for the vial stopper + one for the injection site each day.
References

  • Journal of Immunology (PMC)

    Little peptide, big effects: the role of LL-37 in inflammation and autoimmune disease

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  • Innate Immunity (PMC)

    Antimicrobial peptide LL-37 ameliorates a murine sepsis model via microvesicle release from neutrophils

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  • Wound Repair and Regeneration (PMC)

    Evaluation of LL-37 in healing of hard-to-heal venous leg ulcers: a multicentric prospective RCT

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  • Archives of Dermatological Research (PMC)

    Efficacy of LL-37 cream in enhancing healing of diabetic foot ulcer: a randomized double-blind controlled trial

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  • Bachem Knowledge Center

    Handling and storage guidelines for peptides

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  • CDC One & Only Campaign

    One needle, one syringe, only one time (injection safety)

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  • Johns Hopkins Arthritis Center

    How to give a subcutaneous injection (site selection, rotation)

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  • PubMed / Journal of Steroid Biochemistry

    Vitamin D and the antimicrobial peptide cathelicidin (LL-37)

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  • MedlinePlus (NIH)

    Subcutaneous (SQ) injections: patient instructions

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  • CDC

    Vaccine administration: subcutaneous injection (angle/site; no aspiration)

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  • NCBI Bookshelf

    Best practices for injection (asepsis, preparation, and administration)

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  • Clinical Pharmacology & Therapeutics (PMC)

    Subcutaneous drug injection review: pharmacologic considerations

    View source

Educational content adapted from peptidedosages.com. Not medical advice.