Peptide Companion
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Peptide Companion
single
Healing & Recovery
Vial: 2 mg

PEG MGF (2 mg Vial)

PEG MGF is a pegylated variant of mechano-growth factor, a muscle-derived IGF-1 splice isoform that is upregulated after mechanical stress or injury. The unique C-terminal E peptide of MGF activates muscle satellite cells and local protein synthesis, initiating tissue repair and growth in addition to IGF-1 receptor signaling. This educational protocol presents a once-daily subcutaneous approach using a practical dilution for clear insulin-syringe measurements.

Detailed protocol below.

Dosing Schedule
WeekDaily Dose (mcg)Units (per injection) (mL)
Weeks 1–2200 mcg30 units (0.30 mL)
Weeks 3–4300 mcg45 units (0.45 mL)
Weeks 5–6400 mcg60 units (0.60 mL)
Weeks 7–8500 mcg75 units (0.75 mL)
Supplies Needed
  • •Peptide Vials (PEG MGF, 2 mg each):
  • •Insulin Syringes (U-100):
  • •Bacteriostatic Water (10 mL bottles): Use ~3.0 mL per vial for reconstitution.
  • •Alcohol Swabs: One for the vial stopper + one for the injection site each day.
References

  • Physiological Society

    MGF: a local growth factor or a local tissue repair factor?

    View source

  • In Vivo (PubMed)

    Expression of IGF-1 isoforms after exercise-induced muscle damage in humans: characterization of the MGF E peptide actions in vitro

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  • International Orthopaedics (PubMed)

    Mechano growth factor E peptide promotes osteoblasts proliferation and bone-defect healing in rabbits

    View source

  • American Journal of Transplantation (PubMed)

    A synthetic mechano growth factor E peptide enhances myogenic precursor cell transplantation success

    View source

  • Frontiers in Physiology (PubMed)

    Impaired skeletal muscle regeneration induced by macrophage depletion could be partly ameliorated by MGF injection

    View source

  • Cureus

    Peptide Therapy (News article on Mechano-Growth Factor)

    View source

  • Rapid Communications in Mass Spectrometry (PubMed)

    Characterization and identification of a C-terminal amidated mechano growth factor (MGF) analogue in black market products

    View source

  • CDC

    Chapter 6: Vaccine Administration (Epidemiology and Prevention of Vaccine-Preventable Diseases, 14th ed.)

    View source

  • Cleveland Clinic

    Lipohypertrophy: Symptoms, Causes, Treatment & Prevention

    View source

  • East Carolina University College of Nursing

    Administering Subcutaneous Injections (Clinical Nursing Skills)

    View source

  • Bachem

    Handling and Storage Guidelines for Peptides

    View source

Educational content adapted from peptidedosages.com. Not medical advice.