Semax (10 mg Vial)
Semax is a synthetic heptapeptide analog of ACTH(4–10) developed in Russia and studied primarily for cognitive enhancement and neuroprotection. While intranasal administration is most common in clinical literature, subcutaneous injection offers a convenient once‑daily alternative for research purposes. This educational protocol presents a practical SC approach using straightforward reconstitution for accurate insulin‑syringe measurements.
- Dose
- 0.3–0.6 mg per injection
- Frequency
- Once or twice daily
- Timing
- Morning and/or afternoon
- Duration
- 4–8 weeks
Nootropic peptide. Enhances focus and cognitive function. BDNF upregulation.
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
|---|---|---|
| Weeks 1–2 | 300 mcg | 9 units (0.09 mL) |
| Weeks 3–4 | 500 mcg | 15 units (0.15 mL) |
| Weeks 5–6 | 600 mcg | 18 units (0.18 mL) |
| Weeks 7–8 | 800 mcg | 24 units (0.24 mL) |
- •Peptide Vials (Semax, 10 mg each):
- •Insulin Syringes (U‑100):
- •Bacteriostatic Water (10 mL bottles): Use ~3.0 mL per vial for reconstitution.
- •Alcohol Swabs: One for the vial stopper + one for the injection site each day.
Neuroscience and Behavioral Physiology (Springer)
Comparative study of Semax administration routes (intranasal vs. subcutaneous) in animal models
View sourceVidal Drug Reference (Russia)
Official prescribing information for Semax 0.1% intranasal drops; human dosing guidelines and administration schedules
View sourceJournal of Neurology and Psychiatry (Russia)
Clinical trial of Semax in ischemic stroke patients (6,000 mcg/day intranasal protocol with cycling)
View sourcePeptides.org
Semax dosage overview, cycling recommendations, and protocol duration guidance
View sourceJournal of Higher Nervous Activity (Russia)
Early human study introducing Semax’s nootropic properties and mechanism of action
View sourceVestnik Oftalmologii (Russian Ophthalmology Journal)
Human study of Semax in glaucomatous optic neuropathy; 30‑day safety data
View sourceJohns Hopkins Arthritis Center
Clinical guide to subcutaneous injection technique (preparation, angle, site rotation)
View sourceCDC
Vaccine administration guidelines for subcutaneous injections (angle, no aspiration)
View sourcePharmaceutics (MDPI)
Overview of Russian peptide drugs including Semax; formulation stability and storage considerations
View sourceDrug Testing and Analysis (Wiley)
Review of nootropic peptides including Semax; discussion of human intranasal use patterns
View source
Educational content adapted from peptidedosages.com. Not medical advice.